The Fat Cell Adenylate Cyclase System: Characterization and Manipulation of Its Biomodal Regulation by GTP
- Title:
- The Fat Cell Adenylate Cyclase System: Characterization and Manipulation of Its Biomodal Regulation by GTP
- Creator:
-
Schlegel, Werner
Lin, Michael C.
Cooper, Dermot M.F.
Rodbell, Martin, 1925-1998 - Date:
- 25 September 1979
- Description:
- The second of two articles in which Rodbell indicated that in addition to transducing hormone signals across the membrane, the G-protein could also inhibit signaling at the discriminator point. He provided evidence that G-proteins at the cellular receptors were sophisticated enough to both inhibit and activate signal transduction.
- Periodical:
- Journal of Biological Chemistry
- Publisher:
- American Society for Biochemistry and Molecular Biology
- Location:
- Box: 19. Folder: 9
- Rights:
- Reproduced with permission of the American Society for Biochemistry and Molecular Biology.
- Genre:
- Articles
- Subject:
- Adenylyl Cyclases, Cell Membrane, and Guanosine Triphosphate
- Format:
- Text
- Extent:
- 5 pages
- Relation:
- Letter from Joshua Lederberg to Michael Doudoroff, 1949
- Language:
- English
- Legacy Source Citation:
- Periodical. Cooper, Dermot M. F., Werner Schlegel, Michael C. Lin, and Martin Rodbell. "The Fat Cell Adenylate Cyclase System: Characterization and Manipulation of Its Biomodal Regulation by GTP." Journal of Biological Chemistry 254, 18 (25 September 1979): 8927-8931. Article. 5 Images.. Journal of Biological Chemistry
- Legacy ID:
- GGAABC
- NLM ID:
- 101584917X29
- Profiles Collection:
- The Martin Rodbell Papers
- Shareable Link:
- https://profiles.nlm.nih.gov/101584917X29
- Story Section:
- Signal Transduction and the Discovery of G-Proteins, 1969-1980