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Martin Rodbell - Profiles in Science
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Martin Rodbell
The Martin Rodbell Papers
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Early Work in Cellular Metabolism, 1956-1969
Signal Transduction and the Discovery of G-Proteins, 1969-1980
Cells as "Programmable Messengers," 1981-1994
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Adenylyl Cyclases
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1.
5'-Guanylylimidodiphosphate, A Potent Activator of Adenylate Cyclase Systems in Eukaryotic Cells
Date:
August 1974
2.
Fig[ure]. 1: 1967 Conceptualization of an Hormone-Sensitive Adenylyl Cyclase
Date:
[ca. 1990]
3.
Fig[ure]. 2: 1969 Conceptualization of Adenylyl Cyclase System Stimulated by Multiple Hormones
Date:
[ca. 1990]
4.
Fig[ure]. 3: Early 1970 Representation of the Hormone Sensitive Adenylyl Cyclase As a System Formed of Three Functional Elements: Discriminator, Transducer, and Amplifier
Date:
[ca. 1990]
5.
Fig[ure]. 5: 1977 Model of Hormonal Stimulation of an Adenylyl Cyclase System
Date:
[ca. 1990]
6.
Fig[ure]. 6: 1984 Model of Adenylyl Cyclase System Susceptible to Both Stimulatory and Inhibitory Regulation
Date:
[ca. 1990]
7.
Figure 4: Late 1970 Model of the Glucagon-Sensitive Liver Membrane Adenylyl Cyclase As an Information Transfer System
Date:
[ca. 1990]
8.
GTP Stimulates and Inhibits Adenylate Cyclase in Fat Cell Membranes through Distinct Regulatory Processes
Date:
25 November 1977
9.
Letter from Martin Rodbell to Andre DeLean
Date:
19 August 1980
10.
Letter from Martin Rodbell to Anil Joshi
Date:
15 November 1973
11.
Letter from Martin Rodbell to Peter F. Hall
Date:
30 November 1979
12.
Signal Transduction in Biological Membranes
Date:
1985
13.
Signal Transduction: A Twenty Year History of G-Proteins
Date:
[ca. 1990]
14.
Signal Transduction: Evolution of an Idea
Date:
1995
15.
The Fat Cell Adenylate Cyclase System: Characterization and Manipulation of Its Biomodal Regulation by GTP
Date:
25 September 1979
16.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: I. Properties
Date:
25 March 1971
17.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: II. Comparison Between Glucagon- and Fluoride-Stimulated Activities
Date:
25 March 1971
18.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: III. Binding of Glucagon: Method of Assay and Specificity
Date:
25 March 1971
19.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: IV. Effects of Guanyl Nucleotides on Binding of 125 I-Glucagon
Date:
25 March 1971
20.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: V. An Obligatory Role of Guanyl Nucleotides in Glucagon Action
Date:
25 March 1971
21.
The Metabolism of Isolated Fat Cells: I. Effects of Hormones on Glucose Metabolism and Lipolysis
Date:
February 1964
22.
The Role of Hormone Receptors and GTP-Regulatory Proteins in Membrane Transduction
Date:
6 March 1980