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Martin Rodbell - Profiles in Science
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Martin Rodbell
The Martin Rodbell Papers
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Early Work in Cellular Metabolism, 1956-1969
Signal Transduction and the Discovery of G-Proteins, 1969-1980
Cells as "Programmable Messengers," 1981-1994
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Adenylyl Cyclases
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1.
5'-Guanylylimidodiphosphate, A Potent Activator of Adenylate Cyclase Systems in Eukaryotic Cells
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Fig[ure]. 1: 1967 Conceptualization of an Hormone-Sensitive Adenylyl Cyclase
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3.
Fig[ure]. 2: 1969 Conceptualization of Adenylyl Cyclase System Stimulated by Multiple Hormones
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Fig[ure]. 3: Early 1970 Representation of the Hormone Sensitive Adenylyl Cyclase As a System Formed of Three Functional Elements: Discriminator, Transducer, and Amplifier
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Fig[ure]. 5: 1977 Model of Hormonal Stimulation of an Adenylyl Cyclase System
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Fig[ure]. 6: 1984 Model of Adenylyl Cyclase System Susceptible to Both Stimulatory and Inhibitory Regulation
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7.
Figure 4: Late 1970 Model of the Glucagon-Sensitive Liver Membrane Adenylyl Cyclase As an Information Transfer System
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8.
GTP Stimulates and Inhibits Adenylate Cyclase in Fat Cell Membranes through Distinct Regulatory Processes
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9.
Letter from Martin Rodbell to Andre DeLean
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10.
Letter from Martin Rodbell to Anil Joshi
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11.
Letter from Martin Rodbell to Peter F. Hall
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12.
Signal Transduction in Biological Membranes
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13.
Signal Transduction: A Twenty Year History of G-Proteins
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14.
Signal Transduction: Evolution of an Idea
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15.
The Fat Cell Adenylate Cyclase System: Characterization and Manipulation of Its Biomodal Regulation by GTP
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16.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: I. Properties
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17.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: II. Comparison Between Glucagon- and Fluoride-Stimulated Activities
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18.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: III. Binding of Glucagon: Method of Assay and Specificity
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19.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: IV. Effects of Guanyl Nucleotides on Binding of 125 I-Glucagon
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20.
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: V. An Obligatory Role of Guanyl Nucleotides in Glucagon Action
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21.
The Metabolism of Isolated Fat Cells: I. Effects of Hormones on Glucose Metabolism and Lipolysis
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22.
The Role of Hormone Receptors and GTP-Regulatory Proteins in Membrane Transduction
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